细胞信号传导是近年来生命科学研究的热点之一。有关蛋白转录后修饰 (如蛋白质磷酸化、乙酰化、糖基化等 ) ,信号肽序列测定 ,信号传导途径和多通道调节方式 ,蛋白自折叠及构象变化 ,小分子脂类信号分子等研究由于质谱技术的快速发展而取得了突破性的进展 Cell signaling is one of the hot topics in life science research in recent years. Studies on the post-translational modification of proteins (such as protein phosphorylation, acetylation, glycosylation, etc.), determination of signal peptide sequences, signal transduction pathway and multi-channel regulation, self-folding of proteins and conformational changes, small molecule lipid signaling molecules Mass spectrometry technology has made rapid progress in breakthroughs