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本文调查了182例肺癌病人及200例非肿瘤病人(对照组)的癌症家族史,分析结果:①肺癌组家族患癌率为19.2%,其中直系亲属占94%,对照组家族患癌率为20%,其中直系亲属占85%,肺癌组直系亲属患癌比例大于对照组,提示:肺癌的发病与遗传因素可能有相关性。②将三种不同组织类型肺癌病人的家族患癌率作了比较,小细胞肺癌(Sclc)组最高为26.6%,其次是腺癌21%,鳞癌最低为10%,提示Sclc很可能与癌遗传因素有关。
This paper investigated the family history of cancer in 182 patients with lung cancer and 200 patients with non-tumor (control group) .Results: ①The incidence of family cancer in lung cancer group was 19.2%, of which 94% were immediate family members and family members of cancer in control group The rate was 20%, of which 85% were immediate family members, and the proportion of cancer in immediate family members of lung cancer patients was higher than that in control group, suggesting that the incidence of lung cancer might be related to the genetic factors. The family cancer rates of three different types of lung cancer patients were compared. The highest rate of SCLC was 26.6%, the second was 21% of adenocarcinoma and the lowest was 10% of squamous cell carcinoma, suggesting that Sclc is likely Related to cancer genetic factors.