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目的分析支气管扩张合并哮喘临床治疗的方法和效果。方法本研究选取2013年12月—2015年7月98例重症支气管哮喘患者为对象,将其按照随机数字表法随机分组,分为参比组和综合组各49例。参比组患者予以常规呼吸内科药物干预,在常规治疗同时综合组患者辅以激素吸入、无创正压通气、纤维支气管镜(纤支镜)吸痰等综合干预。对比分析两组患者治疗效果和第一秒用力呼气量(forced expiratory volume in one second,FEV1)、用力肺活量(forced vital capacity,FVC)、肺活量(vital capacity,VC)、呼气峰流速(peak expiratory flow,PEF)等肺功能指标的差异性,计量资料采用t检验,计数资料采用χ2检验,P<0.05为差异有统计学意义。结果治疗后肺功能FEV1、FVC、VC、PEF各指标参比组分别为(1.53±0.42)、(2.43±0.65)、(1.53±0.40)L和(216.40±35.45)L/min,综合组分别为(2.45±0.70)、(2.96±0.73)、(2.90±0.81)L和(253.03±37.83)L/min,综合组各指标均优于参比组,两组对比差异均有统计学意义(均P<0.05)。综合组患者治疗效果为97.96%,明显优于参比组的79.59%,两组对比差异有统计学意义(P<0.05)。结论在常规呼吸内科药物干预的基础上辅以激素吸入、无创正压通气、纤支镜吸痰等综合干预,可有效提高支气管扩张合并哮喘患者治疗效果,改善其肺功能,有助于其预后改善,值得推广。
Objective To analyze the method and effect of clinical treatment of bronchiectasis combined with asthma. Methods A total of 98 patients with severe bronchial asthma from December 2013 to July 2015 were enrolled in this study. They were randomly divided into two groups according to a random number table: 49 cases in each group. The patients in the reference group were given routine respiratory medicine interventions. In the routine treatment, the patients in the combined group were treated with the combination of hormone inhalation, non-invasive positive pressure ventilation, and suction bronchoscopy (bronchofibroscopy). The effects of forced expiratory volume in one second (FEV1), forced vital capacity (FVC), vital capacity (VC) and peak expiratory flow velocity expiratory flow, PEF) and other pulmonary function indicators, measurement data using t test, count data using χ2 test, P <0.05 for the difference was statistically significant. Results After treatment, the indexes of FEV1, FVC, VC and PEF were (1.53 ± 0.42), (2.43 ± 0.65), (1.53 ± 0.40) L and (216.40 ± 35.45) L / (2.45 ± 0.70), (2.96 ± 0.73), (2.90 ± 0.81) L and (253.03 ± 37.83) L / min, respectively. The indexes in the combined group were superior to those in the reference group, with significant differences between the two groups All P <0.05). The treatment effect of the integrated group was 97.96%, which was significantly better than 79.59% of the reference group, the difference between the two groups was statistically significant (P <0.05). Conclusion On the basis of conventional respiratory medicine intervention combined with hormone inhalation, non-invasive positive pressure ventilation, bronchoscopy suction sputum and other comprehensive intervention can effectively improve the treatment of patients with bronchiectasis combined with asthma to improve lung function, contribute to its prognosis Improve, worth promoting.