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目的:探讨补气化瘀颗粒对难治性肾病综合征激素减量维持期临床疗效观察。方法:对难治性肾病综合征通过正规激素与免疫抑制剂治疗后,在激素减量维持治疗期配合中药补气化瘀合剂治疗62例疗效观察。结果:治疗组有效率达93.3%,与对照组比较有显著统计学差异(P<0.05)。结论:补气化瘀颗粒对于难治性肾病综合征激素减量期有比较确切的作用,可以明显减少患者复发频率,保证激素减量过程顺利,临床观察优于单纯西医治疗。其具体机制尚待进一步研究。
Objective: To investigate the clinical effect of Buqi Huayu Granule on maintenance hormone refractory nephrotic syndrome (HNG) maintenance period. Methods: After treatment of refractory nephrotic syndrome with normal hormones and immunosuppressive agents, 62 patients were treated with Chinese medicine Buqi Huayu Mixture in the period of maintenance hormone treatment. Results: The effective rate of the treatment group was 93.3%, which was significantly different from the control group (P <0.05). CONCLUSION: Buqi Huayu Granule has a definite effect on hormone-refractory phase of refractory nephrotic syndrome, which can significantly reduce the frequency of relapse and ensure the smooth process of hormone reduction. The clinical observation is superior to that of western medicine alone. The specific mechanism remains to be further studied.