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目的:探讨艽龙胶囊联合多潘立酮对功能性消化不良患者的临床治疗效果。方法:将83例功能性患者随机分为观察组(42例)和对照组(41例),对照组患者给予多潘立酮口服治疗,观察组患者在此基础上给予艽龙胶囊口服治疗,均连续治疗4周。对两组患者治疗前后临床症状(胃脘饱胀、胃脘烧灼和口干口苦)进行评价,同时观察疗效以及不良反应的发生情况。结果:治疗后两组患者胃脘饱胀、胃脘烧灼和口干口苦等临床症状评分均有明显改善,与同组治疗前比较,差异具有统计学意义(P<0.05),且观察组患者胃脘饱胀、胃脘烧灼和口干口苦评分均低于对照组,组间比较,差异具有统计学意义(P<0.05);观察组患者治疗总有效率95.24%高于对照组80.49%,组间比较,差异具有统计学意义(P<0.05);观察组患者不良反应发生率7.14%与对照组2.44%比较,差异无统计学意义(P>0.05)。结论:艽龙胶囊联合多潘立酮可有效改善功能性消化不良患者胃脘饱胀、胃脘烧灼和口干口苦等临床症状,有效提高治疗效果,且不良反应发生率较低。
Objective: To investigate the effect of Jilong Capsule combined with domperidone on patients with functional dyspepsia. Methods: Eighty-three patients were randomly divided into observation group (n = 42) and control group (n = 41). Patients in the control group were treated with domperidone orally. On the basis of the above data, 4 weeks. Before and after treatment of the two groups of patients with clinical symptoms (stomach fullness, gastric cauterization and mouth dry mouth) were evaluated, and observed the efficacy and adverse reactions. Results: After treatment, the scores of clinical symptoms such as stomach fullness, heartburn cauterization and mouth dryness were significantly improved in both groups, with statistical significance (P <0.05), and the observation group The patients’ gastric cavity fullness, gastric cauterization and dry mouth bitterness scores were lower than the control group, the difference was statistically significant (P <0.05); the total effective rate of the observation group was 95.24% higher than that of the control group 80.49 %, Respectively. The differences between the two groups were statistically significant (P <0.05). The incidence of adverse reactions in the observation group was 7.14% compared with that in the control group (2.44%), with no significant difference (P> 0.05). Conclusion: Jilong Capsule combined with domperidone can effectively improve functional dyspepsia in patients with gastric insufficiency, gastrocnemius and mouth dry mouth and other clinical symptoms, effectively improve the therapeutic effect, and the incidence of adverse reactions is low.