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目的探讨肝硬化患者小肠细菌过度生长情况。方法选择符合入选要求的肝硬化患者60例、慢性乙型肝炎患者40例及20名健康志愿者,采用葡萄糖氢呼气试验诊断小肠细菌过度生长。结果肝硬化患者小肠细菌过度生长发生率为33.3%(20/60),慢性乙型肝炎患者为27.5%(11/40),健康对照组为5%(1/20)。前两者发生率无显著性差别,但都显著高于对照组。结论肝硬化患者存在小肠细菌过度生长,并有较高的发生率。
Objective To investigate the intestinal bacterial overgrowth in patients with cirrhosis. Methods Sixty patients with cirrhosis, 40 patients with chronic hepatitis B and 20 healthy volunteers were enrolled in the study. Glucose hydrogen breath test was used to diagnose intestinal bacterial overgrowth. Results The rate of intestinal bacterial overgrowth in patients with cirrhosis was 33.3% (20/60), that of chronic hepatitis B was 27.5% (11/40), and that of healthy controls was 5% (1/20). The incidence of the former two no significant difference, but were significantly higher than the control group. Conclusion There is a small intestinal bacterial overgrowth in patients with cirrhosis and a high incidence.