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本文测定了183名健康人,52名冠心病和56名高血压患者血清总胆固醇(TC)、高密度脂蛋白-胆固醇(HDL-C)、甘油三酯(TG)含量。冠心病组HDL-C、HDL-C/LDL-C、HDL-C/TC值显著低于健康组(P<0.001)。提示HDL-C为冠心病的“危险降低因子”。高血压病组HDL-C/TC、HDL-C/LDL-C比值显著低于健康组,HDL-C差异不显著。不论TG浓度高、中、低,冠心病发病率均与HDL-C/TC及HDL-C/LDL-C比值呈负相关,与HDL-C呈不规律现象。提示作为冠心病早期预测指标,HDL-C/TC、HDL-C/LDL-C比值比HDL-C及其他脂质水平更有实用价值。
In this study, the serum levels of total cholesterol (TC), high density lipoprotein-cholesterol (HDL-C) and triglyceride (TG) were measured in 183 healthy individuals, 52 coronary heart disease patients and 56 hypertensive patients. HDL-C, HDL-C / LDL-C and HDL-C / TC in CHD group were significantly lower than those in healthy group (P <0.001). Suggesting that HDL-C is a “risk reduction factor” for coronary heart disease. HDL-C / TC, HDL-C / LDL-C ratio in hypertension group was significantly lower than that in healthy group, HDL-C difference was not significant. The incidence of coronary heart disease was negatively correlated with the ratio of HDL-C / TC and HDL-C / LDL-C regardless of the high, medium, low, and high TG concentration, but not with HDL-C. Tip As an early prediction of coronary heart disease, HDL-C / TC, HDL-C / LDL-C ratio than HDL-C and other lipid levels more practical value.