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1乳腺癌前病变的定义和分类1.1癌前病变的定义WHO规定发展成癌肿可能性超过20%的病变为癌前病变。癌前病变大多处于不稳定状态,在某些因素持续作用下可以发生恶变。但是致癌因素一旦解除,也有可能保持稳定或退变或逆转,恢复正常或较正常状态。1.2癌前病变的分类乳腺癌前病变分类尚无一致性意见。最新2012版WHO乳腺肿瘤组织学新分类方法将乳腺癌前病变的组织学分类包括:(1)导管原位癌(DCIS);(2)小叶肿瘤:
1 The definition and classification of breast precancerous lesions 1.1 The definition of precancerous lesions WHO provides the possibility of developing cancer more than 20% of the lesions for the precancerous lesions. Pre-cancerous lesions are mostly in an unstable state, under the constant action of certain factors can occur malignant. However, once the oncogenic factors are relieved, it is possible that they may remain stable or degenerate or reverse, return to normal or normal status. 1.2 Classification of precancerous lesions There is no consensus on the classification of precancerous lesions of breast. The latest 2012 WHO Breast Cancer Histology new classification histological classification of breast precancerous lesions include: (1) ductal carcinoma in situ (DCIS); (2) lobular tumor: