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以柔毛霉素(Daunorubcin)治疗急性早幼粒细胞型白血病,约50％病人取得缓解,平均缓解期为26个月,失败的病例主要由于弥漫性血管内凝血所致之出血,多发生于治疗开始后5天之内,占25％;或者由于败血症,发生于第2～3周,占25％。经柔毛霉素治疗后,急性早幼粒细胞型白血病之存活期,显较其他急性粒细胞型白血病为长。自1967年以后,作者用柔毛霉素治疗44例急性早幼粒细胞型白血病患者。所用方案为:柔毛霉素2毫克/公斤/天或60毫克/平方米/天,注射4天,休息3
In the treatment of acute promyelocytic leukemia with Daunorubcin, about 50% of patients achieved remission with an average remission of 26 months. The failure cases were mainly due to diffuse intravascular coagulation-induced bleeding, which occurred mostly in Within 25 days of the start of treatment, 25%; or due to sepsis occurred in the first 2 to 3 weeks, accounting for 25%. After daunomycin treatment, the survival of acute promyelocytic leukemia, compared with other acute myeloid leukemia is longer. Since 1967, the authors treated 44 patients with acute promyelocytic leukemia with daunorubicin. The regimen used is: 2 mg / kg / day of daunorubicin or 60 mg / m2 / day, 4 days after injection, rest 3