在严重创伤救治过程中,为了预防继发感染常常使用多种抗生素,而且伤情越重,抗生素种类越多,使用量也越大。但是,有些患者却产生了血液细菌培养为阴性,高体温长时间不退、白细胞居高不下等炎性反应。经多年来国内外学者的大量研究,认为此乃“内毒素血症”所致。本文拟从严重创伤 In the course of treatment of severe trauma, multiple antibiotics are frequently used to prevent secondary infection, and the heavier the injury is, the more types of antibiotics are used and the more dosage is used. However, some patients have produced a negative bacterial culture of blood, high temperature for a long time without retreat, high white blood cells and other inflammatory reactions. After many years of domestic and foreign scholars a large number of studies, that this is “endotoxemia” due. This article is to be from a serious trauma