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中药制剂过程蕴藏着中药“毒-效”合和关系,是实现中药“减毒增效”的重要环节。该文从制剂角度阐释中药制剂复方合煎、中药制备工艺、剂型及给药途径、辅料品质等对中药“毒-效”的影响,指出应从中药制剂全过程、基础研究及中药现代制剂角度加强对中药“毒-效”关系的整合分析,探寻制剂过程中“减毒增效”的机制,明确中药制剂在中药“毒与效”中的核心地位,确保中医临床用药的安全性和有效性。
Traditional Chinese medicine process contains the traditional Chinese medicine “poison - effect” and the relationship between the realization of traditional Chinese medicine is “an important part of” attenuation and efficiency “. This article explains the influence of traditional Chinese medicine preparation, traditional Chinese medicine preparation process, dosage form and route of administration, excipient quality on the ”poison - effect“ of traditional Chinese medicine from the perspective of preparation, pointing out that the whole process of traditional Chinese medicine preparation, basic research and modern preparation of traditional Chinese medicine Intensify the integrated analysis of the relationship between ”poison - effect“ of Chinese medicine and explore the mechanism of ”attenuating synergies“ in preparation process, clarify the core position of Chinese medicine preparations in ”poison and effect" of traditional Chinese medicine and ensure that traditional Chinese medicine Clinical medication safety and effectiveness.