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目的研究乳腺癌与妇科肿瘤卵巢癌、子宫内膜癌以及雌激素相关良性肿瘤之间的关系。方法回顾性分析603例乳腺癌患者,经随访调查,分析乳腺癌术后患者目前的生存状况,以及其患妇科肿瘤情况,进一步揭示乳腺癌患者发生妇科肿瘤的危险性是否增加,以及它们之间的内在联系。结果 603例乳腺癌患者中共随访调查到548例,放弃治疗2例,其中手术治疗并规律化疗464例,口服他莫昔芬半年以上者237例,截至到随访日期死亡病例29例;患卵巢癌3例,输卵管癌1例,子宫内膜癌9例;卵巢囊肿14例,子宫肌瘤50例,子宫内膜息肉19例,子宫内膜增生3例。结论乳腺癌与妇科肿瘤之间存在共同的高危因素,如遗传因素以及乳腺癌内分泌治疗药物暴露等环境因素。
Objective To study the relationship between breast cancer and gynecological tumors of ovarian cancer, endometrial cancer and estrogen-related benign tumors. Methods A total of 603 cases of breast cancer were retrospectively analyzed. The follow-up survey was conducted to analyze the current status of postoperative patients with breast cancer and the prevalence of gynecological tumors. It was further revealed whether the risk of gynecologic cancer in breast cancer patients was increased or not, The inner link. Results A total of 548 cases of breast cancer were investigated and 603 cases were given up. Among them, 464 cases were given surgical treatment and regular chemotherapy, 237 cases were treated with tamoxifen for more than half a year, and 29 cases died as of the follow-up date. Patients with ovarian cancer 3 cases, 1 fallopian tube cancer, 9 cases of endometrial cancer; 14 cases of ovarian cysts, 50 cases of uterine fibroids, 19 cases of endometrial polyps, 3 cases of endometrial hyperplasia. Conclusion There are common high risk factors between breast cancer and gynecologic oncology, such as genetic factors and environmental factors such as endocrine therapy of breast cancer.