在医学科学技术蓬勃发展的今天,传统的长期观察法或经验法已不能适用于检验新药的疗效及副作用,临床实验的设计显得越来越重要。“有比较的现代临床试验”方法应运而生。但是,目前这一临床实验技术实际上还没有真正为广大基层医务人员所掌握,为此,笔者就临床科学试验设计的一些至关重要的原则问题简述如下,供同道们参考。一、必须设对照设立对照是一般临床试验必不可少的条件,“有比较才能有鉴别”,这点应该是不难理解的。疾病种类虽多,但多数疾病是可以不药而愈的。如果不设对照,则服某种所试之药后而病愈,人们往往归功于该药,对 With the rapid development of medical science and technology, traditional long-term observation methods or empirical methods can no longer be used to test the efficacy and side effects of new drugs. The design of clinical trials has become increasingly important. “Comparative modern clinical trials” method came into being. However, at present, this clinical experimental technique has not actually been mastered by the vast number of grass-roots medical personnel. For this reason, the author briefly describes some of the most important principles and issues for the design of clinical science experiments for reference by fellow practitioners. First, we must set up a control to set up a comparison is an indispensable condition for general clinical trials, “There are comparisons to be able to identify”, this should not be difficult to understand. Although there are many types of diseases, most diseases can be cured without drugs. If no control is given, the medicine is cured after serving some kind of medicine. People often attribute the medicine to it.