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目的:分析痛风早期肾功能损伤患者的胱抑素C和血清C-反应蛋白检测结果。方法:研究对象为在我院进行治疗的痛风患者100例,其中痛风不伴有肾功能损伤患者50例为第一组,痛风早期肾功能损伤患者50例为第二组。两组均接受全自动生化分析仪进行血清检测,对比两组患者胱抑素C和血清C-反应蛋白。结果:第二组患者胱抑素C和血清C-反应蛋白水平明显高于第一组,(P<0.05)。第二组患者的胱抑素C阳性检出率为76%,血清C-反应蛋白阳性检出率为82%,胱抑素C联合血清C-反应蛋白检测的阳性检出率为90%,(P<0.05)。结论:胱抑素C和血清C-反应蛋白检测能够有效地提升检测阳性检出率,改善痛风患者的预后。
OBJECTIVE: To analyze the results of cystatin C and serum C-reactive protein in patients with early renal dysfunction after gout. Methods: The study included 100 gout patients treated in our hospital. Among them, 50 patients with gout without renal dysfunction were the first group and 50 patients with early gout injury were the second group. Both groups were fully automatic biochemical analyzer for serum testing, comparing the two groups of patients with cystatin C and serum C-reactive protein. Results: The levels of cystatin C and serum C-reactive protein in the second group were significantly higher than those in the first group (P <0.05). In the second group of patients, the positive rate of cystatin C was 76%, the positive rate of serum C-reactive protein was 82%, the positive rate of cystatin C combined with serum C-reactive protein was 90% (P <0.05). Conclusion: Cystatin C and serum C-reactive protein detection can effectively improve the positive detection rate and improve the prognosis of patients with gout.