从尼日利亚普遍用于治疗疟疾的亮叶巴戟(Morinda lucida)的茎皮中,提得一种结晶对小白鼠腹水型180肉瘤具有抑制作用。有效成分的分离:将400克茎皮的粗粉用稀盐酸充分湿润后以乙醚使提取完全,乙醚滤液蒸干,残留物溶于热丙酮中,冷至-20℃3小时后分离,弃去无定形物,将丙酮液蒸干,得一固体,再溶于热乙醚中,随即离心分离弃去无定形物,乙醚液冷至-20℃。 In the bark of Morinda lucida, commonly used in Nigeria for the treatment of malaria, a crystal was found to have an inhibitory effect on mouse ascites 180 sarcoma. The separation of the active ingredient: The 400 g bark of coarse powder with dilute hydrochloric acid fully wetted with ether to make the extraction, the ether was evaporated to dryness, the residue was dissolved in hot acetone, cooled to -20 ℃ 3 hours after the separation, discarded Amorphous, the acetone solution was evaporated to dryness to give a solid, then dissolved in hot ether, then centrifuged to remove the amorphous material, the ether was cooled to -20 ℃.