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目的研究木蹄层孔菌[Fomes fomentarius(L.Ex.Fr.)]的化学成分。方法采用反复硅胶柱色谱法、Sephadex LH-20柱色谱法等进行分离纯化,并通过化合物的理化性质和波谱数据进行结构鉴定。结果从木蹄体积分数95%乙醇提取物中分离得到6个化合物,其中1个木脂素类化合物:泡桐素(1);2个小分子芳香族化合物:原儿茶醛(2),4-(3,4-二羟苯基)-3-丁烯-2-酮(3);3个甾类化合物:5α,8α-过氧化麦角甾-6,22-二烯-3β醇(4),麦角甾-7,22-二烯-3β醇(5),β-谷甾醇(6)。结论化合物1～4,6均为首次从该真菌中分离得到。
Objective To study the chemical constituents of Fomes fomentarius (L.Ex.Fr.). Methods The compounds were isolated and purified by repeated silica gel column chromatography and Sephadex LH-20 column chromatography. Their structures were elucidated by the physicochemical properties and spectral data of the compounds. Results Six compounds were isolated from 95% ethanol extract of hoofed wood, one of which was lipofuscin (1); two small aromatic compounds: protocatechuic aldehyde (2), 4 - 3, 4-dihydroxyphenyl) -3-buten-2-one (3); 3 steroids: 5a, 8a-ergosta-oxalestan-6,22- ), Ergosta-7,22-diene-3β alcohol (5), β-sitosterol (6). Conclusion The compounds 1 ~ 4,6 were isolated from this fungus for the first time.