论文部分内容阅读
目的研究大剂量短疗程左氧氟沙星治疗社区获得性肺炎的疗效和安全性。方法社区获得性肺炎100例随机分为两组,治疗组大剂量短疗程左氧氟沙星治疗,对照组常规治疗。结果治疗组和对照组的痊愈率分别为68%(34/50)和66%(33/50),临床有效率分别为86%(43/50)和84%(42/50),无统计学意义。两组细菌清除率为85.2%(23/27)和84%(21/25),无统计学差异。3d内发热症状的消失率分别为50%和37,5%,具有统计学意义。不良反应的发生率均为8%,无统计学差异。结论大剂量短疗程左氧氟沙星治疗社区获得性肺炎疗效肯定,安全。
Objective To study the efficacy and safety of high dose and short course of levofloxacin in the treatment of community-acquired pneumonia. Methods 100 cases of community-acquired pneumonia were randomly divided into two groups. The treatment group was treated with high-dose and short-term levofloxacin, and the control group was treated routinely. Results The cure rates of the treatment group and the control group were 68% (34/50) and 66% (33/50), respectively. The clinical effective rates were 86% (43/50) and 84% (42/50) respectively, with no statistic Significance of learning. Two groups of bacteria clearance rate was 85.2% (23/27) and 84% (21/25), no significant difference. 3d disappearance of fever symptoms were 50% and 37,5%, with statistical significance. The incidence of adverse reactions were 8%, no statistically significant difference. Conclusion High-dose and short-course levofloxacin treatment of community-acquired pneumonia is effective and safe.