研究了选择性胃肠道抗生素清扫对脓毒血症动物生存率及器官功能的效用。实验用78只雄性Wistar大鼠(200～300g),腹腔内注射酵酶多糖制成腹膜炎模型,然后随机分为4组。甲用药组(14只)和对照组(12只)分别在实验前5天每天2次,实验始0～12天每天1次口服2.5ml甲氧苄啶溶液(20g/L)或相应的水;乙用药组(26只)和对照组(26只)以同样方式分别口服2.5ml链霉素溶液(25g/L)或相应的 The effects of selective gastrointestinal antibiotic cleaning on survival and organ function in septic mice were studied. In this experiment, 78 male Wistar rats (200-300g) were used to make peritonitis model by intraperitoneal injection of glycoprotein and then randomly divided into 4 groups. A group (14 mice) and a control group (12 mice) were treated with 2.5ml trimethoprim solution (20g / L) or the corresponding water once daily for 0-12 days ; Group B (26) and control group (26) were treated with 2.5 ml streptomycin solution (25 g / L) orally or in the same way