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目的:评价四黄水蜜外敷联合三阶梯止痛治疗原发性肝癌介入栓塞后腹痛的疗效及安全性。方法:50例原发性肝癌患者行介入化疗栓塞后,治疗组应用四黄水蜜外敷联合三阶梯止痛药物治疗,对照组仅应用三阶梯止痛药物治疗。介入治疗后3天评价两组止痛疗效及不良反应发生率。结果:治疗后两组疼痛强度与治疗前比较均明显降低,有明显差异(P<0.05)。治疗后疼痛强度治疗组比对照组低,两组之间有明显差异(P<0.05)。治疗组不良反应发生率明显低于对照组(P<0.05)。结论:四黄水蜜外敷与三阶梯止痛药物联合应用,能加强其止痛效果,可有效地治疗原发性肝癌介入栓塞后腹痛,且不良反应发生率低,值得临床推广。
Objective: To evaluate the curative effect and safety of Sihuangshuimong topical three-step analgesia in the treatment of abdominal pain after primary liver cancer interventional embolization. Methods: After interventional chemoembolization in 50 patients with primary hepatic carcinoma, the treatment group was treated with Sihuang Shuimi topical combined with three-step analgesic drugs and the control group with only three-step analgesic drugs. Three days after interventional treatment, the analgesic efficacy and incidence of adverse reactions in both groups were evaluated. Results: The pain intensity of the two groups after treatment was significantly lower than that before treatment, with significant difference (P <0.05). After treatment, the pain intensity was lower in the treatment group than in the control group, with significant difference between the two groups (P <0.05). The incidence of adverse reactions in the treatment group was significantly lower than that in the control group (P <0.05). CONCLUSION: The combination of Sihuang Shuidong external application and three-step analgesic drugs can enhance its analgesic effect and effectively treat abdominal pain after primary liver cancer interventional embolization with low incidence of adverse reactions, which is worthy of clinical promotion.