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自从1963年苏联的Abelev在移植肝癌的小鼠血中发现胚胎蛋白——甲胎蛋白以来,胚胎蛋白在癌诊断中的作用受到了人们重视,随后报告了许多种这类蛋白质.碱性胚胎蛋白(Basic Fetoprotein)是作者1974年在人胎血清和胎儿肠组织提取液中发现的一种新蛋白质,与已知的胚胎蛋白的不同点在于:它不是酸性蛋白而是碱性蛋白;临床上不是用于特定脏器的癌诊断而用于广范围的多种癌的诊断,亦即可用于机体患癌的诊断.由于该蛋白有碱性蛋白的特征,故称为碱性胚胎蛋白(以下简称BFP).
The role of embryonic proteins in the diagnosis of cancers has gained considerable attention since Abelev of the Soviet Union in 1963 discovered mouse embryonic fibroblasts in the blood of mice transplanted with liver cancer and subsequently reported on many of these proteins. (Basic Fetoprotein) is a new protein discovered by the author in human fetal serum and fetal gut tissue in 1974. The difference from the known embryonic protein is that it is not an acidic protein but a basic protein; it is not clinically It is used for the diagnosis of a wide range of cancers and can be used for the diagnosis of cancer in the body due to the diagnosis of cancers in specific organs. Since this protein has the characteristics of alkaline protein, it is called alkaline embryo protein BFP).