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当生产中有害因子的水平和浓度已经降到或接近最高容许值时所引起的疾病,其病因和发病机制,主要是由于各种因子的联合作用。但有关这方面的病理学研究报导尚不多。毫无疑问,这方面研究对于职业病理学、劳动卫生学、工业毒理学均很重要,而且对解决早期诊断和劳动能力鉴定中经常遇到的难题也有帮助。目前看来,根据有害因子分别制订的卫生标准,往往有提出重新审订的必要。本文综合多年来关于联合作用的研究成果。指出,在小型铸钢车间振动和接近容许浓度的锰,对清整工产生协同致病作用。清整工临床锰中毒的平均工龄同含锰很高的熔炼车间接近(6.7和7.1年)。强体力劳动结合低浓度锰作用,也有相同结果(平均中毒工龄为8.1年)。
When the level and concentration of harmful factors in production has dropped to or near the maximum allowable value caused by the disease, its etiology and pathogenesis, mainly due to the combination of various factors. However, there are not many reports of pathological studies in this area. Undoubtedly, research in this area is very important for occupational pathology, occupational hygiene and industrial toxicology. It is also helpful to solve the problems often encountered in the early diagnosis and identification of working ability. At present, according to the health standards formulated respectively according to the harmful factors, there is often a need to propose re-examination. This article synthesizes the research results on the synergistic effect over the years. Pointed out that vibration and close to the allowable concentration of manganese in a small steel plant, synergistic pathogenic cleaning agent. The average length of clinical manganese poisoning for cleaners is close to that of high-manganese-bearing smelters (6.7 and 7.1 years). Strong manual work combined with low concentrations of manganese, also have the same result (average poisoning length of 8.1 years).