1922年M ann和Kawamura在动物实验中完成十二指肠切除,并观察了术后动物的生理状况,未发现明显损害。于20世纪60年代起临床上有少数病例报道。1984年S il-lin等[1]以狗为实验对象,切除约95%的十二指肠,并系统的研究术后生理、代谢及组织学方面改变,证明了单纯切除大部分十二指 In 1922 M ann and Kawamura performed duodenal resection in animal experiments and observed the physiological status of the animals after the operation, and no obvious damage was found. In the 1960s there are a few cases of clinical reports. 1984 S il-lin et al [1] to dogs as the experimental object, resection of about 95% of the duodenum, and systematic study of postoperative physiology, metabolism and histological changes, proved that the simple removal of most of the twelve fingers