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目的探讨近两年南方高热高湿沿海地区念珠菌性阴道炎群体在不同季节、年龄、月经周期的发病情况以及治疗后稳定趋势状况。方法对妇科门诊就诊的8 099例阴道炎患者进行念珠菌检测,采用生理盐水涂片法和革兰染色及念珠菌培养。结果南方高热高湿沿海地区念珠菌性阴道炎发病率为24.694%(2000/8 099);育龄妇女患病率高于其他年龄段,差异有统计学意义(χ2=58.81,P<0.01);夏、秋比冬、春季节患病率高,差异有统计学意义(χ2=32.39,P<0.01);月经后1周患病率高于其它时期,差异有统计学意义(χ2=4.67,P<0.05);治疗后,阳性率随末次用药时间的延长而逐渐下降(趋势χ2=47.78,P<0.01)。结论南方高热高湿沿海地区念珠菌性阴道炎的感染率有所上升;与生育年龄呈正相关;夏、秋季节念珠菌性阴道炎的感染率高;月经后1周,念珠菌的阳性率最高,应重点预防。复查应选停药5 d后,因其结果趋于稳定。
Objective To investigate the incidence of Candida vaginitis in different seasons, ages and menstrual cycles in the hot and humid coastal areas of South China in recent years and the trend of post-treatment stabilization. Methods Candidiasis was detected in 8099 cases of vaginitis in gynecology clinics. The specimens were stained with saline and cultured in Gram stain and Candida. Results The prevalence of Candida vaginitis was 24.694% (2000/8 099) in the coastal areas with high heat, humidity and humid in South China. The prevalence of Candida vaginitis was higher in women of childbearing age than in other age groups (χ2 = 58.81, P <0.01). The prevalence rates in summer, autumn than in winter and spring were higher (χ2 = 32.39, P <0.01), and the prevalence rate at 1 week after menstruation was higher than that in other periods (χ2 = 4.67, P <0.05). After treatment, the positive rate gradually decreased with the prolongation of the last treatment time (χ2 = 47.78, P <0.01). Conclusions The prevalence of Candida vaginitis in the hot and humid coastal areas of the South China is increasing, and it is positively related to the childbearing age. The prevalence of Candida vaginitis is high in summer and autumn. The positive rate of Candida is the highest one week after menstruation , Should focus on prevention. Review should be discontinued after 5 d, due to the results tend to be stable.