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目的:探讨黄芪注射液和巴曲抗栓酶合用对脑梗死的疗效。方法:102 例经CT 证实的脑梗死病人分2 组,常规治疗组48 例( 男性34 例,女性14例,年龄54 a ±s 5 a) 给予20 % 甘露醇250 ~500mL/d ×5 ~7 d 、巴曲抗栓酶d 1 用10 BU,d 3 和d 5用5 BU、胞磷胆碱1 .0 ~1 .5 g/d ×10 ~14 d 均静脉滴注;黄芪组54 例( 男性33 例,女性21 例,年龄54a±6 a) 在常规治疗的基础上加用黄芪注射液30 ~40 m L/d , 静脉滴注10 ~14 d。结果:黄芪组和常规治疗组治疗前及治疗后wk 1 ,2 ,4 末的神经功能缺损评分分别为:20 分±9 分和20 分±11 分( P>0 .05) ;12 分±8 分和14 分±9 分( P> 0 .05) ;9 分±10 分和13 分±9 分( P< 0 .05) ;5 分±6 分和9分±11 分( P< 0 .01) ; 黄芪组的总显效率明显高于常规治疗组( 分别为67 % 和27 % ,P< 0 .01) 。结论:黄芪注射液和巴曲抗栓酶合用使脑梗死病人的近期总显效率明显提高。
Objective: To investigate the curative effect of combined astragalus injection and batroxobin on cerebral infarction. Methods: A total of 102 patients with cerebral infarction confirmed by CT were divided into two groups. 48 patients (34 males and 14 females, age 54 ± 5 years) were given 20% mannitol 250 ~ 500mL / d × 5 ~ 7 d, and batroxobin d 1 with 10 BU, d 3 and d 5 with 5 BU, citicoline 1. 0 ~ 1. 5 g / d × 10 ~ 14 d were intravenous infusion; Astragalus group of 54 patients (33 males and 21 females, age 54a ± 6 a) on the basis of conventional treatment with astragalus injection 30 ~ 40 m L / d, intravenous infusion of 10 ~ 14 d. Results: The scores of neurological impairment at the end of wk 1, 2 and 4 before and after treatment in astragalus group and conventional treatment group were 20 ± 9 and 20 ± 11 respectively (P> 0.05) 8 points and 14 points ± 9 points (P> 0.05); 9 points ± 10 points and 13 points ± 9 points (P <0.05); 5 points ± 6 points and 9 points ± 11 points .01). The total effective rate of Astragalus membranaceus group was significantly higher than that of the conventional treatment group (67% and 27% respectively, P <0.01). Conclusion: Astragalus injection and batroxobin combined with cerebral infarction patients in the recent significant increase in total effective rate.