宫颈癌患者外周血淋巴细胞染色体的数目及结构均发生明显的异常。患者细胞中二倍体的数目只占72.95%,亚二倍体及超二倍体细胞比例明显升高。患者染色体结构畸变率约为正常人的3倍,其中环形染色体、双着丝点、染色单体断裂、染色体易位重组明显增多。经放射线治疗后,染色体的数目及结构异常与放疗前相比有显著改变,说明放射线虽可杀伤肿瘤细胞,但对正常细胞也有较严重的损伤作用。 Cervical cancer patients with peripheral blood lymphocyte chromosome number and structure were significant abnormalities. The number of diploid cells in patients accounted for only 72.95%, sub-diploid and diploid cells increased significantly. Patients with chromosome aberration rate of about three times the normal, including circular chromosomes, dinoflares, chromatid cleavage, chromosomal translocation and reorganization increased significantly. After radiotherapy, chromosome number and structural abnormalities compared with before radiotherapy have significant changes, indicating that although the radiation can kill tumor cells, but also have more serious damage to normal cells.