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介绍利用中效原理设计电脑程序分析化疗联合用药体外药敏实验的效应。本程序所需要的试验次数较少,不但能确定两种药物是否协同,而且能分析药物剂量变化时联合效应的变化情况。可为癌症化疗个体化治疗方案的制定提供参考。
The effect of in vitro susceptibility testing of chemotherapy combined with drugs was designed using the principle of intermediate efficiency design. The number of trials required by this procedure is less, and it is not only possible to determine whether the two drugs are synergistic, but also to analyze the changes in the combined effects when the drug dose changes. Can provide a reference for the development of personalized chemotherapy treatment plan for cancer chemotherapy.