测定34例分泌性中耳炎患者中耳积液与皿浆内毒素含量,并以22例正常人血浆内毒素含量作对照。结果为:患者中耳积液内毒素均值(X±SE)为629.4±99.1ng/L,是血浆内毒素(46.4±6.7ng/L)的13.6倍,p<0.01;94％的患者中耳积液内毒素值超过正常人血浆内毒素含量上限。表明分泌性中耳炎中耳积液定量测定,较之定性测定和细菌培养,更具敏感、精确、简便、快速等优点,对估计预后和临床用药有指导意义。 34 cases of secretory otitis media in the middle ear effusion and dish endotoxin content, and 22 cases of normal plasma endotoxin content as a control. The results were as follows: mean (X ± SE) of middle ear effusion was 629.4 ± 99.1ng / L, which was 13.6 times of that of endotoxin in plasma (46.4 ± 6.7ng / L), p <0.01; 94% of middle ear Endotoxin effusion value exceeds the normal plasma endotoxin content limit. It shows that the quantitative determination of middle ear effusion of otitis media with effusion is more sensitive, accurate, simple and rapid than the qualitative determination and bacterial culture, which is of guiding significance in estimating prognosis and clinical medication.