目的　研究VX2 移植性肝癌模型的特点及螺旋CT监测的价值。方法　将兔VX2 瘤组织块混于生理盐水中,经开腹注入 45只新西兰大白兔的肝左、肝右或肝中叶内,接种后的不同时期行CT平扫加增强双期扫描。结果　在 45只兔中有 40只接种成功,原位成瘤率为 88. 8%,其中肝脏单发结节有 25只,多发结节 15只,分别占 62. 5%、37. 5%,原位成瘤伴有异位种植的有 9只。CT检查平扫表现为低密度或等密度,增强扫描动脉期表现为高密度,门脉期为低密度,肿瘤边缘增强, 2周内阳性率为 46. 7%,第 3周为 90. 0%,不同时期检出率有统计学差异(χ2 =4.12,Ρ<0.05)。结论　经开腹注射法制造肝癌模型是一种简单、易行的方法,但易发生异位种植和多发结节,CT平扫加增强是一种准确可靠的监测方法。 Objective To study the characteristics of VX2 transplanted liver cancer model and the value of spiral CT. Methods Rabbit VX2 tumor tissue was mixed with normal saline, and 45 New Zealand white rabbits were injected into the left hepatic, right hepatic or middle hepatic lobule by laparotomy. CT scan and enhanced double-phase scan were performed at different stages after inoculation. Results Forty-five rabbits were inoculated successfully and the in-situ tumorigenic rate was 88.8%, of which 25 were single solitary nodules and 15 were multiple nodules, accounting for 62.5% and 37.5% , In situ tumor with ectopic planting of 9. 7%, 第 3 周 为 90. 0%. CT scan showed low density or isopycnic density, enhanced scanning arterial phase showed high density, portal phase was low density, enhanced tumor margins, 2 weeks positive rate was 46.7%, the third week was 90.0 %, The detection rate in different periods has statistical difference (χ2 = 4.12, P <0.05). Conclusions The hepatic carcinoma model is a simple and easy method to make by laparotomy. However, ectopic implantation and multiple nodules are easy to occur. CT scan and contrast enhancement is an accurate and reliable monitoring method.