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目的:探讨原发性醛固酮增多症合并肾癌的临床特征、诊断思路与治疗方案,以提高临床医师对此病的认识及诊治能力。方法:观察1例原发性醛固酮增多症合并肾癌的临床特征及诊治过程,结合国内外相关病例的临床特点,总结并复习相关文献。结果:6例患者均行手术治疗,5例患者术后血压及血钾水平均恢复至正常范围,1例单纯肾癌根治术的患者术后血压波动于135-145/80-90 mm Hg。结论:原发性醛固酮增多症合并肾癌比较少见,可借助影像学及实验检查进行鉴别诊断,病理检查可以明确诊断,治疗上建议手术治疗。
Objective: To investigate the clinical features, diagnosis and treatment of primary aldosteronism complicated with renal cell carcinoma in order to improve the understanding and diagnosis and treatment of clinicians. Methods: To observe the clinical features, diagnosis and treatment of one case of primary aldosteronism complicated with renal cell carcinoma, and to summarize and review the relevant literature with the clinical features of related cases at home and abroad. Results: All the 6 patients underwent surgery. The postoperative blood pressure and serum potassium level of 5 patients returned to their normal range. One patient with radical nephrectomy had a postoperative blood pressure fluctuation of 135-145 / 80-90 mm Hg. Conclusion: Primary aldosteronism with renal cell carcinoma is relatively rare, can make use of imaging and laboratory tests for differential diagnosis, pathological examination can confirm the diagnosis and treatment of the proposed surgical treatment.