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急性心肌梗塞(AMI)患者,缺血心肌再灌注时常出现室性心律失常。然而心律失常发生过程及特征却未曾有过研究,本文于静脉链激酶溶栓后即刻及出院前,以24小时动态心电图监测,对AMI患者进行了研究。方法:AMI 45(男35、女10)例,平均年龄59±12(32~75)岁,均符合以下条件:(1)胸痛<3小时;(2)至少2个导联ST段抬高;(3)含硝酸甘油后仍持续胸痛及ST段抬高;(4)无溶栓或抗凝禁忌。尔后所有患者均证实有AMI。于出现胸痛后2.5±1.3(1~4)小时,静脉滴注链激酶750000单位,其中未表现再灌注征象的18
In patients with acute myocardial infarction (AMI), ventricular arrhythmias often occur during reperfusion of ischemic myocardium. However, the process and characteristics of arrhythmia have not been studied. In this paper, AMI patients were studied immediately after intravenous streptokinase thrombolysis and before discharge from hospital with 24-hour Holter monitoring. Methods: AMI 45 (35 males and 10 females) with an average age of 59 ± 12 (32-75) years of age were eligible for the following conditions: (1) chest pain <3 hours; (2) ST segment elevation in at least 2 leads ; (3) with chest pain and ST-segment elevation after treatment with nitroglycerin; (4) no contraindication to thrombolysis or anticoagulation. All patients later confirmed AMI. In the post-chest pain 2.5 ± 1.3 (1 ~ 4) hours, intravenous infusion of streptokinase 750000 units, which did not show signs of reperfusion 18