顶体素(acrosin)是存在于精子顶体内膜上的胰蛋白酶样蛋白水解酶,具有溶解卵透明带使精子通过等作用,在受精过程中极为重要。此酶自本世纪60年代后半期才逐渐了解。据报道,不孕症占已婚夫妇的1/10,其中约半数原因在男性。因此,了解男性的生育能力十分重要。既往对男性生育力的评 Acrosin is a trypsin-like protease present in the acrosin of the spermatozoa. It has the function of dissolving the zona pellucida and passing the sperm through it, and is extremely important during fertilization. This enzyme has been gradually understood since the second half of the 1960s. It has been reported that infertility accounts for one-tenth of a married couple, about half of whom are men. It is therefore important to understand the fertility of men. Past comments on male fertility