患者，女，25岁。因掌跖部皮疹1周就诊。1周前掌跖部出现皮疹，不痛不痒，未予理会。后皮疹逐渐增多。无全身不适。无发热、咽痛、头痛。否认性乱史。询问其夫有不洁性交史。皮肤科情况：掌跖部见多个暗红色丘疹、呈疣状，表面呈松解状脱屑，触之较硬实，无压病，躯干四肢未见 Patient, female, 25 years old. 1 week treatment due to palmar and plantar rash. A week ago, the palms and soles appeared rash, itching, did not care. After the rash gradually increased. No systemic discomfort. No fever, sore throat, headache. Deny sexual chaos history. Ask her husband a dirty history of sexual intercourse. Dermatology: Palmoplantar see a number of dark red papules, verrucous, the surface was loose like desquamation, touch the more hard, no pressure disease, the trunk of the limbs were not seen