脑梗死的发生与血小板功能异常密切相关,脑梗死时血栓状态的研究在该病的预防和治疗上有重要价值。本文报道脑梗死患者血浆血小板α颗粒膜蛋白-140(GMP-140)、6-酮-前列环素_(1α)(6-k-PGF_(1α))、血栓素B_2(TXB_2)的变化,以了解老年脑梗死患者中血小板功能变化及其临床意义。 1 对象与方法 1.1 对象 急性脑梗死患者26例,其中男24例,女2例,年龄为60～88岁。所有病例的诊断均符合第2次全国脑血管病学术会议第3次修订的标准,且均经头颅CT(和)或核 The occurrence of cerebral infarction and platelet dysfunction are closely related to the study of thrombotic state of cerebral infarction in the prevention and treatment of the disease have important value. This article reports the changes of plasma platelet α-granule membrane protein-140 (GMP-140), 6-keto-prostacyclin (6α) and TXB_2 in patients with cerebral infarction To understand the changes of platelet function in elderly patients with cerebral infarction and its clinical significance. 1 Subjects and Methods 1.1 Subjects 26 patients with acute cerebral infarction, including 24 males and 2 females, aged 60 to 88 years. All cases were diagnosed in line with the 2nd National Cerebrovascular Disease Conference revised the third standard, and are by head CT (and) or nuclear