早期研究表明,异氟醚可引起冠状动脉窃血现象,因而不主张用于冠心病患者。但近年来的研究证实,只要冠脉的灌注压正常,异氟醚并不引起冠状动脉窃血及心肌缺血,且认为异氟醚可降低心肌缺血再灌注损伤、降低心肌梗死面积保护心脏。因此,只要冠脉灌注压正常,异氟醚在冠心病患者的麻醉中有明显的优势。 Early studies have shown that isoflurane can cause coronary steal phenomenon, which is not advocated for coronary heart disease patients. However, recent studies confirm that isoflurane does not cause coronary steal and myocardial ischemia as long as coronary perfusion pressure is normal, and that isoflurane can reduce myocardial ischemia-reperfusion injury and reduce the area of ​​myocardial infarction to protect the heart . Therefore, as long as normal coronary perfusion pressure, isoflurane in patients with coronary artery disease has obvious advantages in anesthesia.