颅内感染临床探析

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目的:分析探讨近两年来我院收治的颅内感染患者分布情况,该疾病的主要临床特点、治疗措施及其预后,为全面科学的诊断治疗本病提供线索,供临床参考使用。方法:对我院2010年1月至2012年12月间收治的以颅内感染诊断并治疗的患者97例的临床资料进行回顾性总结和分析,总结颅内感染的发病情况、人群分布特点以及主要的致病菌和预后情况。结果:本组97例患者中男性66例,女性31例,男女发病比例为2.13:1;发病人群以学龄前儿童最为多见,共计73例,占到了75.26%;其中有39例为乙型病毒性脑炎,发病率最高,占40.21%;其次为结核杆菌所致脑膜炎,共计27例,占27.84%;第三位是脑膜炎双球菌引起的脑炎,共计23例,占23.71%;其余8例中有7例为革兰氏阴性杆菌感染,占7.22%,1例革兰氏阳性菌感染所致,占1.03%;根据GOS预后评分,恢复良好者60例、中度残疾17例、重度残疾11例、植物状态1例和死亡9例。结论:颅内感染是学龄前儿童群体中常见的严重疾病之一,特别以乙型病毒性脑炎最为多见,早期及时就医,准确诊断和积极治疗是保证预后的关键。 Objective: To analyze the distribution of patients with intracranial infection treated in our hospital in recent two years, the main clinical features, treatment measures and prognosis of the disease, provide clues for the comprehensive and scientific diagnosis and treatment of this disease for clinical reference. Methods: The clinical data of 97 patients with intracranial infection diagnosed and treated from January 2010 to December 2012 in our hospital were retrospectively reviewed and analyzed. The incidence of intracranial infection, the distribution characteristics of the population, The main pathogens and prognosis. Results: There were 66 males and 31 females in this group of 97 patients, the incidence rate of male to female was 2.13: 1. The most common incidence of preschool children was 73 cases, accounting for 75.26% of them; 39 of them were type B Viral encephalitis, the highest incidence, accounting for 40.21%; followed by meningitis caused by Mycobacterium tuberculosis, a total of 27 cases, accounting for 27.84%; the third is meningococcal encephalitis, a total of 23 cases, accounting for 23.71% ; The remaining 8 cases of Gram-negative bacilli in 7 cases, accounting for 7.22%, 1 case of gram-positive bacteria caused by infection, accounting for 1.03%; according to the GOS prognostic score, 60 cases of good recovery, moderate disability 17 Cases, severe disability in 11 cases, 1 case of plant status and 9 cases of death. Conclusion: Intracranial infection is one of the most common serious diseases in preschool children. Especially for the most common type B viral encephalitis, early and timely medical treatment, accurate diagnosis and active treatment are the keys to guarantee the prognosis.
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