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生物素(Biofin)是一种辅酶,是羧酶(Carboxylase)组成成分,与体内二氧化碳的固定有关。在营养不足时生物素并不会缺乏,这是因为肠道内微生物能够产生以供机体需要。很早以前就了解,如果给鼠喂养蛋白,会发生生物素缺乏。因为他们能与肠道内生物素相结合而使得生物素不能被吸收。Mock等叙述一婴儿因大小肠大部切除后给予补液三月,先在面部,以后扩散到全身的红疹,体毛丧失、苍白、易激惹、昏睡和肌张力轻度降低。化验检查血中生物素水平降低,尿内羧酶活力不足。
Biofin is a coenzyme that is a component of the carboxylase that is involved in the immobilization of carbon dioxide in the body. Biotin is not lacking in undernutrition because the gut micro-organisms can be produced for the body’s needs. It is well understood long ago that biotin deficiency occurs when mice are fed protein. Because they can combine with the intestinal biotin so that biotin can not be absorbed. Mock et al. Described a mild loss of rash, loss of body hair, paleness, irritability, lethargy, and mild muscle tension when a baby was given fluid rehydration for most of the large intestine after resection in March. Laboratory tests reduce blood levels of biotin, urinary carboxylase activity is not enough.