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海杧果(Cerbera Odollam)属夹竹桃科植物。印度、澳洲、和我国南部均有分布。早在1864年Devrij曾从其种仁榨出的油中提出一种甙,称为Cerberin。其后Greshoff又分出一种与Cerberin不同的水溶性甙,称为 Odollin。Plugge证明Cerberin及海杧果的粗制剂均能引起蛙心收缩期停止。陈克恢亦自印度海忙果中提出Cerberin与Cerberoside,并研究了它们的药理作用。近年来袁青禄等研究了国产海杧果酸制剂的强心作用及其生物活性,证明它有明显的强心作用,且作用极为迅速。本工作乃采自国产海忙果提出之Cerberin,进一步研究了其
Cerbera Odollam is an Apocynaceae plant. India, Australia, and southern China are all distributed. As early as 1864, Devrij had proposed a glycoside from the oil extracted from its kernels, called Cerberin. Greshoff then split a water-soluble glycoside different from Cerberin, called Odollin. Plugge proved that Cerberin and sea buckthorn crude formulations can cause the frog heart to stop systolic. Chen Ke-Hui also raised Cerberin and Cerberoside from the busy sea of India and studied their pharmacological effects. In recent years, Yuan Qinglu et al studied the cardiac action and biological activity of domestic seaweed acid preparations, proving that it has obvious cardiac effect and its effect is extremely rapid. This work is taken from Cerberin made by Busan, the home-grown company, for further study