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目的分析从小儿烧伤感染患者标本中分离出的病原菌及其耐药性资料,为临床治疗提供参考依据。方法收集某院269例小儿烧伤感染患者(年龄≤8岁)标本中分离出的细菌培养资料,对病原菌分布及药敏结果进行统计分析。结果 (1)共分离出406株病原菌,来源创面感染菌株362株占89.2%;(2)检出病原菌中以革兰阴性菌居多284株(70.0%),其中铜绿假单胞菌102株(25.1%);(3)多重耐药鲍曼不动杆菌(MDR-AB)检出率偏高(67.2%),对米诺环素、替加环素敏感;金黄色葡萄球菌对万古霉素、利奈唑胺、替考拉宁尚未发现耐药。结论小儿烧伤患者最常见的感染为烧伤创面感染,以革兰阴性杆菌为主,鲍曼氏不动杆菌多重耐药性检出率较高。
Objective To analyze the pathogen and drug resistance data isolated from the specimens of children with burn infection and provide a reference for clinical treatment. Methods A total of 269 cases of pediatric burn infection (age ≤ 8 years) in a hospital were collected for bacterial culture, and the distribution of pathogens and susceptibility results were statistically analyzed. Results (1) A total of 406 strains of pathogens were isolated and 362 strains of wound infection were originated from the wounds, accounting for 89.2%. (2) Among the pathogenic bacteria, 284 (70.0%) were Gram-negative bacteria, of which 102 strains were Pseudomonas aeruginosa 25.1%). (3) The detection rate of multidrug-resistant Acinetobacter baumannii (MDR-AB) was high (67.2%), sensitive to minocycline and tigecycline. Staphylococcus aureus Linezolid, teicoplanin have not been found resistant. Conclusions The most common infection in pediatric burn patients is burn wound infection, mainly Gram-negative bacilli, and the detection rate of Acinetobacter baumannii multi-drug resistance is high.