抗体在病毒感染中,除通过中和病毒、介导细胞杀伤起保护作用外,从六十年代开始已发现在某些情况下,还有促进病毒感染的作用。这一现象最早发现于登革热,即在再次感染后,病人可发生比一般感染更为严重的出血热症状,并已被证实与抗体有关。此后,在西尼罗河热、黄热病、Murray河谷 Antibodies have been shown to play a protective role in virus infection in addition to protecting cells by neutralizing the virus and mediating cell killing, and in some cases since the 1960s, it has been found that there is also a role for promoting viral infection. This phenomenon was first found in dengue fever, that is, after the re-infection, the patient may develop more severe symptoms of hemorrhagic fever than the general infection and has been proved to be related to the antibody. Since then, the West Nile fever, yellow fever, Murray River Valley