“百疼丹”胶囊Ⅰ、Ⅱ、Ⅲ号方系临床经验方,具有舒筋活血、消炎止痛、祛风散湿、消除骨刺等功效,临床上用于腰腿痛、风湿病、坐骨神经痛等多种病症的治疗,效果显著。我们对其镇痛、抗炎的药效学进行了研究,现报告如下。1 实验材料1.1 动物 昆明小鼠,雌雄各半,体重19g～23g;Wistar大鼠,雌雄各半,体重130g～150g。由北京医科大学实验动物中心提供。1.2 药物 “百疼丹”Ⅰ、Ⅱ、Ⅲ号方由河南开封光明医院提供,实验时去除胶囊外壳,取其药粉,于匀浆器中研至极细,加蒸馏水分别配制成0.041g/ml、0.082g/ml浓度的药液;醋酸 The clinical experience of the “Baihandan” capsules I, II, and III prescriptions has the effects of easing muscles and promoting blood circulation, reducing inflammation, relieving pain, dispelling dampness, removing spurs, etc. Clinically, it is used for low back pain, rheumatism, sciatica, etc. The treatment of various diseases has significant effects. We have studied its analgesic and anti-inflammatory pharmacodynamics. The report is as follows. 1 Experimental Materials 1.1 Animals Kunming mice, male and female, weighing 19g-23g; Wistar rats, male and female, weighing 130g-150g. Provided by Experimental Animal Center of Beijing Medical University. 1.2 The drugs “Baihandan” I, II, and III were provided by the Guangming Hospital of Kaifeng, Henan Province. During the experiment, the capsule shell was removed, and the powder was taken. The powder was homogenized in a homogenizer and added to distilled water to make 0.041g/ml, 0.082 respectively. g/ml concentration of the liquid; acetic acid