目的探讨分析左卡尼汀联合血液透析治疗尿毒症性周围神经病变的临床疗效。方法回顾性分析2013年10月至2015年12月76例尿毒症性周围神经病变患者的临床资料。结果治疗组总有效率为91.49%,治疗后正中神经传导速度为(49.32±5.29)m/s,胫神经传导速度为(47.03±4.18)m/s,腓总神经传导速度为(42.93±4.88)m/s,均优于对照组,差异均有统计学意义(P<0.05)。结论左卡尼汀联合血液透析治疗尿毒症性周围神经病变的临床疗效显著,值得临床推广应用。 Objective To investigate the clinical efficacy of levocarnitine combined with hemodialysis in the treatment of uremic peripheral neuropathy. Methods The clinical data of 76 patients with uremic peripheral neuropathy from October 2013 to December 2015 were retrospectively analyzed. Results The total effective rate was 91.49% in the treatment group. The median nerve conduction velocity was (49.32 ± 5.29) m / s, the tibial nerve conduction velocity was (47.03 ± 4.18) m / s and the common peroneal nerve conduction velocity was (42.93 ± 4.88) ) m / s, were better than the control group, the differences were statistically significant (P <0.05). Conclusion Lcakitin combined with hemodialysis treatment of uremic peripheral neuropathy significant clinical effect, it is worthy of clinical application.