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目的:观察S-腺苷蛋氨酸(思美泰)联合茵陈注射液治疗乙型肝炎高胆红素血症的临床效果。方法:选择慢性乙型肝炎高胆红素血症70例,分为观察组40例和对照组30例。对照组予茵陈注射液治疗,观察组在此基础上加用思美泰治疗,比较两组治疗前后症状改善情况、有效率及胆红素下降速度。结果:两组治疗后症状改善及有效率差异不显著(P>0.05);但观察组显效率及TBil、TBA平均每天下降幅度显著优于对照组(P<0.05)。结论:思美泰联合茵陈注射液治疗乙型肝炎高胆红素血症效果优于单用复方茵陈注射液。
Objective: To observe the clinical effect of S-adenosylmethionine combined with Yinchen injection in the treatment of hepatitis B hyperbilirubinaemia. Methods: Seventy patients with chronic hepatitis B with hyperbilirubinemia were divided into observation group (40 cases) and control group (30 cases). The control group was infused with Yinchen injection. On the basis of this, the observation group was treated with Simmel, and the improvement of symptoms, efficiency and rate of decline of bilirubin were compared between the two groups before and after treatment. Results: There was no significant difference between the two groups in symptom improvement and effective rate (P> 0.05). However, the effective rate of TBil and TBA in observation group was significantly lower than that in control group (P <0.05). Conclusion: Smectite combination Yinchen injection in treating hepatitis B hyperbilirubinemia is better than compound Yinchen injection.