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随着核能发展及核电站运转,释放到环境中的氚越来越多。通过食物链转移,对人类影响越来越引起人们的关注。近来,国内外学者对氚的危害进行了较多的研究。如氚水诱发小鼠外周血淋巴细胞微核细胞率;胎肝中嗜多染红细胞(PCE)微核细胞率等其出现随剂量升高而升高。与~(60)Coγ射线诱发的微核细胞率作比较,测得了氚RBE值。为了进一步研究低水平氚水诱发的细胞遗传学效应,本实验选用低水平氚水,观察了小鼠骨髓中PCE微核细胞率变化,并测得氚RBE值。
With the development of nuclear power and the operation of nuclear power plants, more and more tritium is released into the environment. The impact on human beings has drawn more and more attention through the food chain transfer. Recently, domestic and foreign scholars have done more research on the harm of tritium. Such as tritiated water-induced mouse peripheral blood lymphocyte micronuclei rate; fetal liver polychromatic erythrocyte (PCE) micronuclei rate increased with increasing doses. Compared with the rate of ~ (60) Coγ-ray-induced micronuclei, tritium RBE value was measured. In order to further study the cytogenetic effect induced by low level of tritiated water, low tritiated water was used in this experiment to observe the changes of PCE micronuclei in mouse bone marrow and the tritium RBE value was measured.