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转化生长因子 - β(transform ing growth factor- β,TGF- β)最初是由 Roberts等 [1 ] 学者在 1981年作为一个可诱导大鼠肾成纤维细胞增殖的因子描述的。随着对其研究的不断深入 ,现已知它是一个对各种细胞具有刺激或抑制作用的多功能细胞因子。它通过自分泌或旁分泌 ,在调节
Transforming growth factor-β (TGF-β) was originally described by Roberts et al [1] in 1981 as a factor that induces the proliferation of rat renal fibroblasts. With the deepening of its research, it is now known that it is a multi-functional cytokine that stimulates or suppresses various kinds of cells. It regulates by autocrine or paracrine