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目的:针对消化性溃疡出血症状应用西咪替丁和兰索拉唑治疗的临床效果研究。方法:随机选出阳春市潭水中心卫生院2015年1月至2017年1月消化道内科收治的50例消化性溃疡出血患者作为究对象,并随机、平均将患者分成观察组和对照组,且每组25例。观察组的患者行兰索拉唑治疗,对照组患者行西咪替丁治疗,最终对比两组患者的临床疗效。结果:观察组与对照组总有效率分别为96.0%~64.0%,观察组高于对照组,差异具有统计学意义(P<0.05);观察组凝血及疼痛消失时间低于对照组,差异具有统计学意义(P<0.05)。治疗完成后,观察组胃内pH值、复发状况指标与对照组比较,差异均无统计学意义(P>0.05)。结论:在消化性溃疡出血症状的治疗中,西咪替丁与兰索拉唑均具有一定的治疗效果,但兰索拉唑的临床治疗效果更加明显。
Objective: To study the clinical effect of cimetidine and lansoprazole in treating peptic ulcer bleeding. Methods: Fifty patients with peptic ulcer hemorrhage treated by Department of Gastroenterology, Yangchun Water and Sanitary Hospital from January 2015 to January 2017 were selected randomly and divided into observation group and control group randomly. And each group of 25 cases. Patients in the observation group were treated with lansoprazole, and patients in the control group were treated with cimetidine. The clinical efficacy of the two groups was finally compared. Results: The total effective rate of the observation group and the control group was 96.0% ~ 64.0%, the observation group was higher than the control group, the difference was statistically significant (P <0.05); the coagulation and pain disappear time in the observation group was lower than that of the control group Statistical significance (P <0.05). After treatment, the intragastric pH value and recurrence index in the observation group were not significantly different from those in the control group (P> 0.05). CONCLUSION: Both cimetidine and lansoprazole have certain curative effect in the treatment of peptic ulcer bleeding, but the clinical effect of lansoprazole is more obvious.