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为了探讨不同类型肾脏疾病与肾性骨病发生发展的关系,对1991年1~11月诊治的63例肾脏病患者用单光子吸收法(spA)测定尺、桡骨远端1/3处骨矿含量(BMC)。63例肾脏病患者按其肌酐清除率分A、B、C3组。对比分析发现:BMC测定值,A组27例中有24例降低,B组21例中有8例降低,C组全部在正常范围;BMC测定值A、C组间差异显著(P<0.05),B、C组间无显著差异(P>0.05).说明BMC测定值降低幅度与肌酐清除率的下降有显著的正相关系,血液透析时间与BMC的降低幅度呈显著正相关。作者建议,可将BMC测定用于临床监测慢性肾功能不全患者的骨代谢紊乱。
In order to explore the relationship between different types of kidney disease and the development of renal osteodystrophy, 63 patients with kidney disease diagnosed and treated from January 1991 to November 1991 were examined by single-photon absorption spectroscopy (SPA) Content (BMC). 63 cases of patients with kidney disease according to their creatinine clearance rate points A, B, C3 group. The results of BMC analysis showed that in group B, 24 cases were reduced in 27 cases, 8 cases in group B were reduced in 8 cases and group C was all in normal range. There was significant difference between group B and group B (P <0.05). 05), there was no significant difference between B and C groups (P> 0.05). This shows that there is a significant positive correlation between the decrease of BMC and the decrease of creatinine clearance. The hemodialysis time has a significant positive correlation with the decrease of BMC. The authors suggest that BMC assays may be used clinically to monitor bone metabolism disorders in patients with chronic renal insufficiency.