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诊断标准:黄体中期(经前5～10天)血清孕酮水平(RIA法测定)低于15ng/ml.本组69例不孕病人(72%为原发不孕)测得的值为4～14ng/ml.治疗方法:采用阶梯形递增方式的克罗米芬.从月经第三天(原文如此)开始服用.第一周期剂量为5mg/天×5天.在黄体中期测定血清孕酮水平作监护.以后逐月增加剂量(每月增加50mg/天)直至黄体中期血清孕酮水平达到或超过20ng/ml或每日克罗米芬的剂量达150mg.如克罗米芬剂量增至100或150mg/天时黄体中期孕酮水平仍不足,则在月经周期第十五天或十六天加用绒毛膜促性腺激
Diagnostic criteria: serum progesterone levels (measured by RIA method) of less than 15 ng / ml in the mid luteal phase (5 to 10 days before menstruation) were measured in 69 infertile patients (72% of primary infertility) ~ 14ng / ml. Treatment: Clomiphene in a step-shaped incremental manner from the third day of menstruation (the original text so) to start taking the first cycle dose of 5mg / day × 5 days in the mid luteal serum progesterone level Custody.After the monthly increase in dose (50mg / day increase) until the mid luteal phase of serum progesterone at or above 20ng / ml or clomiphene citrate dose of 150mg.If clomiphene dose increased to 100 or 150mg / day when the corpus luteum Medium-term progesterone levels are still not enough, then in the menstrual cycle on the fifteenth day or sixteen plus chorionic gonadotropin