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透析是治疗终末期肾功能衰竭病人常用的有效疗法。特别是近几年来持续性非卧床腹膜透析(CAPD)的开展,使腹膜透析更广泛地应用于临床。虽然透析技术、卫生设施等都有了明显的改善。但腹膜炎的发生仍成为腹膜透析的一个重要的并发症。反复的腹腔感染已成为长期进行腹膜透析的障碍。因此抗生素的合理应用便成为成功地进行腹膜透析的一个重要因素。关于抗菌素的种类、给药途径、剂量、给药方案的选择等目前尚无一致意见,现对近年来腹膜透析并发感染时抗菌素应用的几个问题进行综述。
Dialysis is a commonly used effective treatment for patients with end-stage renal failure. Especially in recent years, continuous ambulatory peritoneal dialysis (CAPD) carried out to make peritoneal dialysis more widely used in clinical. Although dialysis technology, sanitation facilities have been significantly improved. But the occurrence of peritonitis is still an important complication of peritoneal dialysis. Repeated intra-abdominal infection has become a long-term peritoneal dialysis obstacles. Therefore, the rational use of antibiotics has become an important factor in the successful peritoneal dialysis. There is currently no consensus on the types of antibiotics, the route of administration, the dosage, the choice of dosage regimen, and so forth. Several issues concerning the application of antibiotics in peritoneal dialysis in recent years are reviewed.