遗传性痉挛性截瘫(hereditary spastic paraplegia)是一种锥体束变性疾病,具有明显家族性、遗传性。国外Bayley等及Bremer均相继有报告。国内林世和等亦有本病家系及病例报告。但迄今为止,国内外文献还未见有该病的大家系调查。我院在1983年5月发现一个大家系,现报告如下。 Hereditary spastic paraplegia is a pyramidal tract degenerative disease with obvious familial, hereditary. Foreign Bayley, etc. and Bremer have been reported. Domestic Lin Shihe also have the pedigree and case reports. However, up to now, no literature has been found in domestic and foreign literature to investigate the disease. Our hospital found a family in May 1983, the report is as follows.