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目的:对木犀科丁香属植物紫丁香叶的化学成分进行研究。方法:采用硅胶柱色谱法、重结晶及制备高效液相色谱等技术提取分离,利用紫外(UV)、红外(IR)、质谱(EI-MS)、核磁共振(1H-NMR,13C-NMR)、异核多量子关系谱(HMQC)及多键碳氢关系谱(HMBC)等光谱方法鉴定化合物结构。结果:分析并鉴定了9个化合物的结构:(+)松脂素-4″-O-β-D-葡萄吡喃糖苷(1),(+)表松脂素-4-O-β-D-葡萄糖苷(2),落叶松脂醇-4-O-β-D-葡萄吡喃糖苷(3),3,4∶3’,4’-bis(methylene-dioxy)-9’-hydroxyl-lignane-9-methyl-O-β-D-葡萄吡喃糖苷(4),2-(3,4-dihydroxyphenyl)ethyl(1R,4aS,8R,8aS)-8-methyl-6-oxo-1-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethy)oxan-2-yl]oxy-4a,5,8,8a-tetrahydro-1H-pyrano[3,4-c]pyran-4-carboxylate(5),3,4-二羟基苯乙二醇(6),对羟基苯乙醇(7),6-O-(E)-feruloyl-(α)-glucopyranoside(8),6-O-(E)-feruloyl-(β)-glucopyranoside(9)。结论:化合物1～6为首次从该植物分离得到的化合物。
OBJECTIVE: To study the chemical constituents of Syringa Lilium leaves. Methods: The constituents were isolated and purified by silica gel column chromatography, recrystallization and preparative HPLC. The compounds were characterized by UV, IR, EI-MS, 1H-NMR and 13C-NMR. , Heteronuclear multiple quantum correlation spectroscopy (HMQC) and multi-bond hydrocarbon relationship spectroscopy (HMBC) were used to identify the structures of the compounds. Results: The structures of nine compounds were analyzed and identified: (+) pinoresin-4 "-O-β-D-glucopyranoside (1) Glucoside (2), Larchone-4-O-β-D-glucopyranoside (3), 3,4: 3 ’, 4’-bis (methylene-dioxy) 9-methyl-O-β-D-glucopyranoside (4), 2- (3,4-dihydroxyphenyl) ethyl (1R, 4aS, 8R, 8aS) 2S, 3R, 4S, 5S, 6R) -3,4,5-trihydroxy-6- (hydroxymethy) oxan- (8), 6-O- (E) -feruloyl- (α) -glucopyranoside (8), pyran-4-carboxylate ), 6-O- (E) -feruloyl- (β) -lucopyranoside (9) .CONCLUSION: Compounds 1-6 are the first compounds isolated from this plant.